Fusion 'TPT1'-'ERBB3' in UCS
5'Gene 3'Gene
Gene Name TPT1 ERBB3
Chromosome 13 12
Strand -1 1
Breakpoint position 45911313 56492035
Discordant read pairs 2
Junction spanning reads 59
Perfect Junction spanning reads 29
BLAST E value 2.8
Tier tier3
Frame 3UTR-5UTR
Centrality -1.0
SampleId TCGA.N6.A4VC.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]
3' Gene erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.