Fusion 'MKL1'-'SERPIND1' in UCS
5'Gene 3'Gene
Gene Name MKL1 SERPIND1
Chromosome 22 22
Strand -1 1
Breakpoint position 40859225 21133585
Discordant read pairs 2
Junction spanning reads 2
Perfect Junction spanning reads 1
BLAST E value 1.4
Tier tier4
Frame CDS-5UTR
Centrality 0.36511
SampleId TCGA.N6.A4VC.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:HGNC:14334]
3' Gene serpin family D member 1 [Source:HGNC Symbol;Acc:HGNC:4838]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.