Fusion 'APPL2'-'TUBA1C' in SARC
5'Gene 3'Gene
Gene Name APPL2 TUBA1C
Chromosome 12 12
Strand -1 1
Breakpoint position 105622903 49663248
Discordant read pairs 15
Junction spanning reads 6
Perfect Junction spanning reads 4
BLAST E value 2.4
Tier tier1
Frame In-frame
Centrality 0.36547
SampleId TCGA.DX.A2IZ.01A
Validated by WGS validated

Fig. The gene expression correlation between fused genes

5' Gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]
3' Gene tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.