Fusion 'CASP10'-'CFLAR' in LUAD
5'Gene 3'Gene
Gene Name CASP10 CFLAR
Chromosome 2 2
Strand 1 1
Breakpoint position 202070696 201994452
Discordant read pairs 2
Junction spanning reads 2
Perfect Junction spanning reads 2
BLAST E value 0.93
Tier tier3
Frame CDS-5UTR
Centrality 0.37568
SampleId TCGA.71.8520.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene caspase 10 [Source:HGNC Symbol;Acc:HGNC:1500]
3' Gene CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.