Fusion 'CLTC'-'ROS1' in LUAD
5'Gene 3'Gene
Gene Name CLTC ROS1
Chromosome 17 6
Strand 1 -1
Breakpoint position 57768072 117642557
Discordant read pairs 53
Junction spanning reads 16
Perfect Junction spanning reads 15
BLAST E value 0.17
Tier tier4
Frame In-frame
Centrality 0.38495
SampleId TCGA.44.2665.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene clathrin heavy chain [Source:HGNC Symbol;Acc:HGNC:2092]
3' Gene ROS proto-oncogene 1, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10261]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.