Fusion 'ARHGEF3'-'ANO10' in LUAD
5'Gene 3'Gene
Gene Name ARHGEF3 ANO10
Chromosome 3 3
Strand -1 -1
Breakpoint position 56807737 43474219
Discordant read pairs 50
Junction spanning reads 28
Perfect Junction spanning reads 25
BLAST E value 1.6
Tier tier1
Frame In-frame
Centrality 0.36049
SampleId TCGA.35.4123.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]
3' Gene anoctamin 10 [Source:HGNC Symbol;Acc:HGNC:25519]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.