Fusion 'HELZ'-'TTYH2' in BRCA
5'Gene 3'Gene
Gene Name HELZ TTYH2
Chromosome 17 17
Strand -1 1
Breakpoint position 65174775 72248373
Discordant read pairs 6
Junction spanning reads 4
Perfect Junction spanning reads 4
BLAST E value 0.52
Tier tier1
Frame Out-of-frame
Centrality 0.35377
SampleId TCGA.OL.A5RZ.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878]
3' Gene tweety family member 2 [Source:HGNC Symbol;Acc:HGNC:13877]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.