Fusion 'APPBP2'-'SEPT9' in BRCA
5'Gene 3'Gene
Gene Name APPBP2 SEPT9
Chromosome 17 17
Strand -1 1
Breakpoint position 58577760 75486824
Discordant read pairs 2
Junction spanning reads 5
Perfect Junction spanning reads 3
BLAST E value 0.29
Tier tier3
Frame In-frame
Centrality -1.0
SampleId TCGA.EW.A2FS.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene amyloid beta precursor protein binding protein 2 [Source:HGNC Symbol;Acc:HGNC:622]
3' Gene septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.