Fusion 'PDE7A'-'PREX2' in BRCA
5'Gene 3'Gene
Gene Name PDE7A PREX2
Chromosome 8 8
Strand -1 1
Breakpoint position 66647029 68950394
Discordant read pairs 16
Junction spanning reads 13
Perfect Junction spanning reads 13
BLAST E value 1.4
Tier tier1
Frame In-frame
Centrality 0.35287
SampleId TCGA.D8.A1XZ.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791]
3' Gene phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:22950]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.