Fusion 'MTBP'-'PQLC2' in BRCA
5'Gene 3'Gene
Gene Name MTBP PQLC2
Chromosome 8 1
Strand 1 1
Breakpoint position 121458753 19651989
Discordant read pairs 5
Junction spanning reads 3
Perfect Junction spanning reads 1
BLAST E value 100.0
Tier tier3
Frame Out-of-frame
Centrality 0.35974
SampleId TCGA.D8.A1XZ.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene MDM2 binding protein [Source:HGNC Symbol;Acc:HGNC:7417]
3' Gene PQ loop repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:26001]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.