Fusion 'CHD6'-'CHRNB4' in BRCA
5'Gene 3'Gene
Gene Name CHD6 CHRNB4
Chromosome 20 15
Strand -1 -1
Breakpoint position 40141485 78923674
Discordant read pairs 2
Junction spanning reads 2
Perfect Junction spanning reads 2
BLAST E value 0.024
Tier tier4
Frame In-frame
Centrality 0.36534
SampleId TCGA.C8.A8HR.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057]
3' Gene cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.