Fusion 'EIF2S2'-'DEFB123' in BRCA
5'Gene 3'Gene
Gene Name EIF2S2 DEFB123
Chromosome 20 20
Strand -1 1
Breakpoint position 32699902 30037832
Discordant read pairs 10
Junction spanning reads 194
Perfect Junction spanning reads 175
BLAST E value 0.52
Tier tier1
Frame Out-of-frame
Centrality 0.36751
SampleId TCGA.C8.A273.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene eukaryotic translation initiation factor 2 subunit beta [Source:HGNC Symbol;Acc:HGNC:3266]
3' Gene defensin beta 123 [Source:HGNC Symbol;Acc:HGNC:18103]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.