Fusion 'CDK12'-'AKAP1' in BRCA
5'Gene 3'Gene
Gene Name CDK12 AKAP1
Chromosome 17 17
Strand 1 1
Breakpoint position 37628016 55187386
Discordant read pairs 10
Junction spanning reads 15
Perfect Junction spanning reads 14
BLAST E value 1.2
Tier tier1
Frame Out-of-frame
Centrality 0.35998
SampleId TCGA.C8.A12M.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene cyclin dependent kinase 12 [Source:HGNC Symbol;Acc:HGNC:24224]
3' Gene A-kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:367]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.