Fusion 'UBA3'-'FRMD4B' in BRCA
5'Gene 3'Gene
Gene Name UBA3 FRMD4B
Chromosome 3 3
Strand -1 -1
Breakpoint position 69120686 69225807
Discordant read pairs 8
Junction spanning reads 12
Perfect Junction spanning reads 12
BLAST E value 0.12
Tier tier1
Frame Out-of-frame
Centrality -1.0
SampleId TCGA.BH.A0WA.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene ubiquitin like modifier activating enzyme 3 [Source:HGNC Symbol;Acc:HGNC:12470]
3' Gene FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.