Fusion 'KLF3'-'SCFD2' in BRCA
5'Gene 3'Gene
Gene Name KLF3 SCFD2
Chromosome 4 4
Strand 1 -1
Breakpoint position 38691500 54011749
Discordant read pairs 3
Junction spanning reads 6
Perfect Junction spanning reads 6
BLAST E value 7.1
Tier tier1
Frame Out-of-frame
Centrality 0.36764
SampleId TCGA.BH.A0WA.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516]
3' Gene sec1 family domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30676]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.