Fusion 'HECTD1'-'PRPF39' in BRCA
5'Gene 3'Gene
Gene Name HECTD1 PRPF39
Chromosome 14 14
Strand -1 1
Breakpoint position 31675003 45564424
Discordant read pairs 8
Junction spanning reads 2
Perfect Junction spanning reads 2
BLAST E value 0.002
Tier tier1
Frame CDS-5UTR
Centrality 0.36289
SampleId TCGA.AR.A0TV.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157]
3' Gene pre-mRNA processing factor 39 [Source:HGNC Symbol;Acc:HGNC:20314]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.