Fusion 'LRCH3'-'MED12L' in BRCA
5'Gene 3'Gene
Gene Name LRCH3 MED12L
Chromosome 3 3
Strand 1 1
Breakpoint position 197544173 150834125
Discordant read pairs 3
Junction spanning reads 2
Perfect Junction spanning reads 2
BLAST E value 0.81
Tier tier1
Frame In-frame
Centrality 0.34455
SampleId TCGA.AO.A0JA.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene leucine rich repeats and calponin homology domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28637]
3' Gene mediator complex subunit 12 like [Source:HGNC Symbol;Acc:HGNC:16050]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.