Fusion 'DIAPH3'-'TDRD3' in BRCA
5'Gene 3'Gene
Gene Name DIAPH3 TDRD3
Chromosome 13 13
Strand -1 1
Breakpoint position 60667762 61141659
Discordant read pairs 162
Junction spanning reads 122
Perfect Junction spanning reads 115
BLAST E value 0.042
Tier tier1
Frame In-frame
Centrality 0.35776
SampleId TCGA.AN.A0FY.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene diaphanous related formin 3 [Source:HGNC Symbol;Acc:HGNC:15480]
3' Gene tudor domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20612]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.