Fusion 'ULK1'-'PRKAR1B' in BRCA
5'Gene 3'Gene
Gene Name ULK1 PRKAR1B
Chromosome 12 7
Strand 1 -1
Breakpoint position 132401607 591107
Discordant read pairs 2
Junction spanning reads 1
Perfect Junction spanning reads 1
BLAST E value 0.039
Tier tier3
Frame Out-of-frame
Centrality -1.0
SampleId TCGA.AC.A2BK.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene unc-51 like autophagy activating kinase 1 [Source:HGNC Symbol;Acc:HGNC:12558]
3' Gene protein kinase cAMP-dependent type I regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9390]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.