Fusion 'THBS2'-'NME4' in BRCA
5'Gene 3'Gene
Gene Name THBS2 NME4
Chromosome 6 16
Strand -1 1
Breakpoint position 169646292 448990
Discordant read pairs 3
Junction spanning reads 3
Perfect Junction spanning reads 3
BLAST E value 0.021
Tier tier1
Frame In-frame
Centrality -1.0
SampleId TCGA.AC.A2BK.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene thrombospondin 2 [Source:HGNC Symbol;Acc:HGNC:11786]
3' Gene NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.