Fusion 'SERINC2'-'ARHGEF1' in BRCA
5'Gene 3'Gene
Chromosome 1 19
Strand 1 1
Breakpoint position 31902385 42398280
Discordant read pairs 5
Junction spanning reads 3
Perfect Junction spanning reads 3
BLAST E value 0.07
Tier tier1
Frame In-frame
Centrality -1.0
SampleId TCGA.AC.A2BK.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene serine incorporator 2 [Source:HGNC Symbol;Acc:HGNC:23231]
3' Gene Rho guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:681]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.