Fusion 'IGFBP5'-'CXCR5' in BRCA
5'Gene 3'Gene
Gene Name IGFBP5 CXCR5
Chromosome 2 11
Strand -1 1
Breakpoint position 217536828 118754475
Discordant read pairs 2
Junction spanning reads 1
Perfect Junction spanning reads 1
BLAST E value 0.28
Tier tier3
Frame 3UTR-5UTR
Centrality 0.36394
SampleId TCGA.A8.A079.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene insulin like growth factor binding protein 5 [Source:HGNC Symbol;Acc:HGNC:5474]
3' Gene C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.