Fusion 'PNPLA6'-'ECSIT' in BRCA
5'Gene 3'Gene
Gene Name PNPLA6 ECSIT
Chromosome 19 19
Strand 1 -1
Breakpoint position 7599125 11618863
Discordant read pairs 10
Junction spanning reads 27
Perfect Junction spanning reads 25
BLAST E value 0.27
Tier tier1
Frame 5UTR-CDS
Centrality 0.36175
SampleId TCGA.A7.A56D.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene patatin like phospholipase domain containing 6 [Source:HGNC Symbol;Acc:HGNC:16268]
3' Gene ECSIT signalling integrator [Source:HGNC Symbol;Acc:HGNC:29548]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.