Fusion 'GDPD1'-'SMG8' in BRCA
5'Gene 3'Gene
Gene Name GDPD1 SMG8
Chromosome 17 17
Strand 1 1
Breakpoint position 57298112 57292166
Discordant read pairs 7
Junction spanning reads 9
Perfect Junction spanning reads 9
BLAST E value 4.6
Tier tier1
Frame Out-of-frame
Centrality 0.32658
SampleId TCGA.A7.A56D.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene glycerophosphodiester phosphodiesterase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20883]
3' Gene SMG8, nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:25551]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.