Fusion 'RAD50'-'TCOF1' in BRCA
5'Gene 3'Gene
Gene Name RAD50 TCOF1
Chromosome 5 5
Strand 1 1
Breakpoint position 131895059 149767465
Discordant read pairs 3
Junction spanning reads 8
Perfect Junction spanning reads 6
BLAST E value 0.35
Tier tier1
Frame In-frame
Centrality -1.0
SampleId TCGA.A2.A0EP.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene RAD50 double strand break repair protein [Source:HGNC Symbol;Acc:HGNC:9816]
3' Gene treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.