Fusion 'LNPEP'-'CAST' in BRCA
5'Gene 3'Gene
Chromosome 5 5
Strand 1 1
Breakpoint position 96271878 96011243
Discordant read pairs 20
Junction spanning reads 30
Perfect Junction spanning reads 28
BLAST E value 0.17
Tier tier1
Frame CDS-5UTR
Centrality 0.37288
SampleId TCGA.A2.A0D2.01A
Validated by WGS validated

Fig. The gene expression correlation between fused genes

5' Gene leucyl and cystinyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:6656]
3' Gene calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.