Fusion 'TYK2'-'CDC37' in BRCA
5'Gene 3'Gene
Gene Name TYK2 CDC37
Chromosome 19 19
Strand -1 -1
Breakpoint position 10488890 10504117
Discordant read pairs 82
Junction spanning reads 34
Perfect Junction spanning reads 29
BLAST E value 0.9
Tier tier1
Frame Out-of-frame
Centrality -1.0
SampleId TCGA.A2.A0D0.01A
Validated by WGS non-validated

Fig. The gene expression correlation between fused genes

5' Gene tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440]
3' Gene cell division cycle 37 [Source:HGNC Symbol;Acc:HGNC:1735]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.