Fusion 'KSR2'-'P2RX4' in BRCA
5'Gene 3'Gene
Gene Name KSR2 P2RX4
Chromosome 12 12
Strand -1 1
Breakpoint position 118198816 121670217
Discordant read pairs 2
Junction spanning reads 3
Perfect Junction spanning reads 3
BLAST E value 1.2
Tier tier2
Frame In-frame
Centrality 0.37658
SampleId TCGA.A2.A0D0.01A
Validated by WGS validated

Fig. The gene expression correlation between fused genes

5' Gene kinase suppressor of ras 2 [Source:HGNC Symbol;Acc:HGNC:18610]
3' Gene purinergic receptor P2X 4 [Source:HGNC Symbol;Acc:HGNC:8535]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.

Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.