Fusion 'IKZF3'-'PNMT' in BRCA
5'Gene 3'Gene
Gene Name IKZF3 PNMT
Chromosome 17 17
Strand -1 1
Breakpoint position 38020373 37825882
Discordant read pairs 305
Junction spanning reads 498
Perfect Junction spanning reads 461
BLAST E value 0.4
Tier tier4
Frame In-frame
Centrality 0.37384
SampleId TCGA.3C.AALI.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene IKAROS family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:13178]
3' Gene phenylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:9160]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.