Fusion 'CWC25'-'PRKAR1A' in BRCA
5'Gene 3'Gene
Gene Name CWC25 PRKAR1A
Chromosome 17 17
Strand -1 1
Breakpoint position 36981419 66511535
Discordant read pairs 16
Junction spanning reads 15
Perfect Junction spanning reads 13
BLAST E value 0.31
Tier tier1
Frame CDS-5UTR
Centrality 0.37003
SampleId TCGA.3C.AALI.01A
Validated by WGS NA

Fig. The gene expression correlation between fused genes

5' Gene CWC25 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:25989]
3' Gene protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388]

Per the recommendation of the HUGO Gene Nomenclature Committee for Gene Fusion Designation, gene fusions are now annotated as "Gene A::Gene B". Please note that the nomenclature in the image below predates these recommendations.


Fig. Exon expression plot for fused genes. Expression was normalized across all exons; blue = lowest expression, red = highest expression. Line indicates where genes are connected.